SCDiag

The principle The test uses a single drop of blood. A smartphone and an artificial-intelligence tool analyse the sample, without bulky equipment or complex reagents. The aim is clear: to enable mass screening, even in resource-limited areas to quickly identify...

PRESEV 1 & PRESEV 2

Introduction Acute chest syndrome (ACS) can develop rapidly after a severe vaso-occlusive crisis (VOC), and its progression can be sudden. Early identification of high-risk patients is therefore a key priority in order to: improve medical management, prevent severe...

PHARE Mayotte

Context During Cyclone Chido, continuity of care for people with sickle cell disease in Mayotte was at risk. With the support of Siclopédie: a medical hotline was set up; remote specialist consultation was activated between Mayotte, Réunion and mainland France; the...

MORPHEO

Why does the same dose of morphine relieve some patients… but not others? The MORPHEO project addresses this key issue. At present, responses to morphine vary greatly from one patient to another: ineffectiveness, adverse effects or overdose may occur. This...

Hydroxyurea and pregnancy

A key question remains: is it safe to use hydroxyurea during pregnancy? This treatment is currently the most effective at reducing complications of sickle cell disease, but it is often discontinued during pregnancy due to a lack of robust scientific data. The HU &...